Coding

Part:BBa_K4407001:Design

Designed by: Leyu Xu   Group: iGEM22_Worldshaper-Nanjing   (2022-09-30)


dps，DNA protection against oxidative damage


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


Design Notes

Oxygen and its active substances, such as H2O2 and O2-, react with Fe2+ in the cell, forming HO·, which could damage DNA. Dps protein prevents Fe2+ from reacting with H2O2. In addition, Dps protein helps maintain manganese homeostasis, as it stores and releases Manganese. We applied this gene to C. tyrobutyricum so that it might enhance the viability of C. tyrobutyricum in aerobic environment.

Source

The source of the part will be its sequence retrieved from GenBank.

References